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The holidays bring a lot of family gatherings. But what if you are trying to stick to a high-protein, low-carb eating style? Here are high-protein low-carb Christmas casseroles to make your life easier during the holidays.
Just because the holidays are here, it doesn’t mean that you need to say goodbye to your health goals.
They are simple to prepare, perfect for feeding a crowd, or if you need to make a meal ahead of time so you can focus on other tasks.

Table of Contents
- 1. Keto Jalapeno Popper Casserole
- 2. Buffalo Chicken Cauliflower Casserole
- 3. Keto Zucchini Beef Casserole
- 4. Keto Chicken Cauliflower Casserole
- 5. Keto Cheesy Philly Casserole
- 6. Low Carb Taco Casserole
- 7. Keto Chicken Bacon Ranch Casserole
- 8. Chicken Broccoli Bake
- 9. Broccoli Cauliflower Casserole
- 10. Keto Chicken and Biscuit Casserole
- 11. Chicken, Ham and Asparagus Casserole
- 12. Low Carb Eggplant Parmesan Casserole
- 13. Broccoli Casserole with Turkey
- 14. Brussels Sprouts Casserole
- 15. Keto Chicken and Vegetable Casserole
- 16. Keto Ground Beef Casserole
- 17. Keto Chicken Fajita Casserole
- 18. Chicken Cordon Bleu Casserole
- 19. Keto Reuben Casserole
- 20. Spaghetti Squash Casserole
- 21. Spinach Artichoke Chicken Casserole
1. Keto Jalapeno Popper Casserole

You love the taste of jalapeno poppers but hate all the effort it takes to make them? This casserole captures all the spicy, creamy, and cheesy goodness in a simple, one-dish meal.
Here, tender chicken blends with a creamy cheese and heavy cream sauce with a kick from diced jalapeños. With 34 grams of protein per serving and less than 5 grams of net carbs, it’s perfect to keep you on your health goals during the holidays.
Per Serving:
- Calories: 438
- Fats: 31g
- Protein: 34g
- Carbs: 5.4g
- Fiber: 0.6g
- Sugar: 2.1g
2. Buffalo Chicken Cauliflower Casserole

Bring some heat to the holidays with this Buffalo chicken cauliflower casserole. It combines the spicy kick of Buffalo sauce with tender shredded chicken and creamy melted cheese, all mixed with riced cauliflower.
This high protein Christmas casserole is easy to assemble, and it only takes 35 minutes to bake, making it a great option if you don’t have a lot of time to cook.
Per Serving:
- Calories: 419
- Fats: 31g
- Protein: 30g
- Carbs: 6g
- Fiber: 1.3g
- Sugar: 2.7g
3. Keto Zucchini Beef Casserole

This cozy winter casserole recipe features savory ground beef, tender zucchini, and a rich, cheesy sauce that comes together in just under 40 minutes. The combination of Italian seasoning, garlic, and onion powder creates a flavorful meal.
It gives you 26 grams of protein and less than 5 grams of net carbs per serving, making it a filling and nutritious meal.
Per Serving:
- Calories: 443
- Fats: 35g
- Protein: 26g
- Carbs: 6.1g
- Fiber: 1.2g
- Sugar: 2.6g
4. Keto Chicken Cauliflower Casserole

Want something indulgent and cheesy? This keto chicken cauliflower casserole combines tender chicken, riced cauliflower, and crispy bacon in a creamy, flavorful sauce.
This is the perfect recipe for those who miss traditional creamy pasta dishes. The cauliflower provides that pasta flavor without all the extra carbs.
Per Serving:
- Calories: 342
- Fats: 27g
- Protein: 21g
- Carbs: 4.6g
- Fiber: 0.6g
- Sugar: 1.5g
5. Keto Cheesy Philly Casserole

Enjoy the classic flavors of a Philly cheesesteak without all the carbs in this keto cheesy Philly casserole. This dish transforms the beloved sandwich into a hearty, low-carb meal.
Each bite offers ground beef, sautéed onions, and bell peppers, all combined in a creamy, cheesy sauce that it’s made from cream cheese and provolone. It gives you 28 grams of protein and less than 5 grams of net carbs per serving.
Per Serving:
- Calories: 338
- Fats: 22g
- Protein: 28g
- Carbs: 6.7g
- Fiber: 1.3g
- Sugar: 2.6g
6. Low Carb Taco Casserole

This low-carb taco casserole is made with seasoned ground beef, cheese, and your favorite taco toppings. It’s a perfect recipe if you want to feed a large crowd and it’s Taco Tuesday.
Each serving gives you 37 grams of protein and less than 10 grams of net carbs. And, the best thing is that you can easily adapt the toppings based on what you and your family like.
Per Serving:
- Calories: 568
- Fats: 40g
- Protein: 37g
- Carbs: 14g
- Fiber: 4.6g
- Sugar: 5.5g
7. Keto Chicken Bacon Ranch Casserole

The classic combination of chicken, bacon, and ranch is going to be a definite crowd-pleaser. Here, you get tender chicken and crispy bacon, all cooked in a creamy ranch-flavored sauce and topped with melted cheese.
This indulgent meal gives you 25 grams of protein and less than 3 grams of net carbs, making it a keto-lovers dream.
Per Serving:
- Calories: 315
- Fats: 22g
- Protein: 25g
- Carbs: 4.2g
- Fiber: 0.9g
- Sugar: 1.8g
8. Chicken Broccoli Bake

This chicken broccoli shows that simple ingredients can create a big impact. The creamy, cheesy sauce will make everyone love eating broccoli.
With 26 grams of protein and less than 6 grams of net carbs, this meal is definitely going to keep you full during the holidays.
Per Serving:
- Calories: 354
- Fats: 24g
- Protein: 26g
- Carbs: 8.9g
- Fiber: 2.4g
- Sugar: 2.8g
9. Broccoli Cauliflower Casserole

This vegetarian casserole is a creamy, cheesy, comforting meal. It can become the perfect side dish for your Christmas dinner, or use it as the main course if you want a plant-based holiday.
The recipe has less than 10 grams of net carbs and 17 grams of protein, proving that plant-based recipes can be equally healthy and delicious.
Per Serving:
- Calories: 388
- Fats: 32g
- Protein: 17g
- Carbs: 12g
- Fiber: 2.4g
- Sugar: 3.6g
10. Keto Chicken and Biscuit Casserole

Source: bobbiskozykitchen.com
If you are craving a classic chicken pot pie, this keto casserole version is going to be the perfect low-carb alternative.
It’s made with creamy chicken and a vegetable filling topped with fluffy, keto-friendly biscuits. It’s an impressive recipe that’s perfect for your special Christmas dinner.
Per Serving:
- Calories: 613
- Fats: 52g
- Protein: 25g
- Carbs: 16g
- Fiber: 5g
- Sugar: 5g
11. Chicken, Ham and Asparagus Casserole

Source: ketocookingwins.com
This elegant (yet comforting) casserole combines chicken, ham, and asparagus in a creamy, savory sauce. The tender asparagus adds a fresh, slightly crisp texture that balances the richness of the meat and sauce.
With 26 grams of protein and only 5 grams of net carbs, it’s a great, balanced meal to offer your family. And, if you want to adapt it, just make a carb-based side (like mashed potatoes) for anyone who is not following a low-carb lifestyle.
Per Serving:
- Calories: 426
- Fats: 34g
- Protein: 26g
- Carbs: 5g
- Fiber: 1g
- Sugar: 2g
12. Low Carb Eggplant Parmesan Casserole

Source: jerseygirlcooks.com
Slices of eggplant are layered with rich marinara sauce, mozzarella, and Parmesan cheese. It’s then placed in the oven to bake until it’s golden.
By skipping the breading on the eggplant, you keep the carb intake low (less than 14 grams of net carbs), while still giving you a good protein intake (28 grams).
Per Serving:
- Calories: 433
- Fats: 28g
- Protein: 28g
- Carbs: 20g
- Fiber: 7g
- Sugar: 11g
13. Broccoli Casserole with Turkey

Source: ketocookingwins.com
If you have some leftover turkey from your Christmas dinner, here is what you can do with it. The turkey and broccoli combine in a creamy, cheesy sauce that turns these simple ingredients into an extraordinary meal.
It’s a high protein and low-carb meal that’s perfect for your post-holiday lunches or dinners.
Per Serving:
- Calories: 287
- Fats: 22g
- Protein: 15g
- Carbs: 8g
- Fiber: 2g
- Sugar: 3g
14. Brussels Sprouts Casserole

Source: simplystacie.net
Not everyone is a fan of Brussels sprouts, but they are going to become a fan when they try this recipe. You cook the sprouts in a creamy cheese sauce with bacon, which transforms this into a savory and indulgent meal.
The combination of smoky bacon, rich cheese, and tender Brussels sprouts is simply irresistible; even picky eaters are going to love it.
Per Serving:
- Calories: 389
- Fats: 31g
- Protein: 20g
- Carbs: 7g
- Fiber: 2g
- Sugar: 2g
15. Keto Chicken and Vegetable Casserole

Source: jenniferbanz.com
This Christmas casserole is a great way to pack a variety of vegetables into your meal. Tender chicken combines with a mix of low-carb vegetables in a savory, creamy sauce.
One of the best things is that it’s a very versatile meal, meaning you can add whichever ingredients you have or like. And, it gives you a whopping 30 grams of protein per serving and less than 6 grams of net carbs.
Per Serving:
- Calories: 410
- Fats: 28g
- Protein: 30g
- Carbs: 8g
- Fiber: 2g
16. Keto Ground Beef Casserole

Source: laraclevenger.com
Simple, hearty, and incredibly flavorful, this keto ground beef casserole is the perfect easy dinner to have before the holiday rush. Seasoned ground beef is baked with a cheesy topping for an incredibly satisfying meal.
And, it’s a great budget-friendly option that gives you 17 grams of protein per serving and less than 2 grams of net carbs.
Per Serving:
- Calories: 290
- Fats: 23g
- Protein: 17g
- Carbs: 3g
- Fiber: 1g
- Sugar: 2g
17. Keto Chicken Fajita Casserole

Source: jenniferbanz.com
All the sizzling flavors of fajitas are made into a convenient cheesy casserole. Tender chicken, bell peppers, and onions, seasoned with fajita spices to give you a flavor kick.
It’s one of the highest protein recipes, with 53 grams of protein per serving. Ideal when you need a protein boost and need to stay full for a long time.
Per Serving:
- Calories: 508
- Fats: 28g
- Protein: 53g
- Carbs: 7g
- Fiber: 1g
18. Chicken Cordon Bleu Casserole

Source: easyhealthllc.com
This is a deconstructed version of the classic chicken Cordon Bleu. Here, you get layers of chicken, ham, and Swiss cheese. And, it has a delicious creamy sauce.
It offers 36 grams of protein per serving and only 3 grams of carbs, making it a great keto-friendly recipe.
Per Serving:
- Calories: 308
- Fats: 16g
- Protein: 36g
- Carbs: 3g
19. Keto Reuben Casserole

Source: jenniferbanz.com
If you love the tangy, savory flavors of a Reuben sandwich, you are in for a treat. Each bite gives you corned beef, sauerkraut, and Swiss cheese with a creamy dressing that captures all the flavors of the beloved dish.
The recipe has 29 grams of protein per serving and only 3 grams of net carbs.
Per Serving:
- Calories: 407
- Fats: 26g
- Protein: 29g
- Carbs: 4g
- Fiber: 1g
20. Spaghetti Squash Casserole

Source: wholesomeyum.com
Craving pasta while you are on a keto journey? This is a great solution!
The tender strands of spaghetti squash give you that pasta feeling without throwing off your carb intake. And, it’s mixed with savory meat and topped with delicious gooey cheese.
Per Serving:
- Calories: 443
- Fats: 34.1g
- Protein: 22.2g
- Carbs: 14.1g
- Fiber: 3.8g
- Sugar: 6.5g
21. Spinach Artichoke Chicken Casserole

Source: ketocookingchristian.com
Here, you get the traditional flavors of spinach and artichoke dish, but in a casserole format. It’s creamy, cheesy, and just so full of flavor that everyone is going to want another bite.
The combination of spinach, artichoke hearts, and chicken creates a delicious, low-carb meal that everyone will enjoy.
Per Serving:
- Calories: 493
- Fats: 35g
- Protein: 37g
- Carbs: 7g
- Fiber: 2g
- Sugar: 2g












