Fall is the perfect season for casseroles. But what’s even better, you can make casseroles that are both high protein but also lower in calories.

All while still having all those delicious fall flavors! I love to make these throughout the cold season because I know it’ll be feeding everyone at home for more than a day.

Although, they do disappear rather quickly. Which definitely makes them my favorite high protein casseroles!

You must try them too! So, here is the list!

1. Jalapeno Popper Casserole

This is the best casserole you’ll ever have. Well, or at least one of them.

It’s delicious, filled with bold flavors, some spice and creaminess. Just the kind of cheesy goodness you might need. I know sure do.

Per Serving:

• Calories: 438
• Fats: 31g
• Protein: 34g
• Carbs: 5.4g
• Fiber: 0.6g
• Sugar: 2.1g

2. Southwest Chicken Casserole

Zesty southwestern spices combine with juicy chicken and fluffy rice in this simple one-dish wonder. Packed with protein and naturally gluten-free, it’s ideal for preparing ahead on busy weeks.

Need dinner sorted fast without sacrificing taste or nutrition? We’ve all been in that spot on hectic evenings when time is tight but you still want something satisfying.

This casserole delivers big, bold flavors while keeping things wholesome and balanced. It’s the kind of recipe that becomes a household staple, the one everyone asks you to make again and again.

Per Serving:

• Calories: 376
• Fats: 10g
• Protein: 37g
• Carbs: 34g
• Fiber: 7.6g
• Sugar: 6.4g

3. Lazy Lasagna Casserole

Imagine all the flavors of traditional lasagna without all the fussy layering. This simplified version of the classic Italian dish offers you 32 grams of protein per serving.

This “lazy” approach to lasagna uses ground beef, ricotta, mozzarella, and a rich tomato sauce. In a matter of no time, you’ll have a delicious casserole dish full of Italian flavors.

Per Serving:

• Calories: 449
• Fats: 22g
• Protein: 32g
• Carbs: 28g
• Fiber: 3.9g
• Sugar: 9.2g

4. Yogurt Monkey Bread Casserole

Most of casseroles are savory and packed with protein but some of them come as a sweet treat! A really nice dessert!

I’ve made this one with a bunch of delicious spices and Greek yogurt, which is why it’s so high in protein and low in calories.f

Per Serving:

• Calories: 90
• Fats: 0.3g
• Protein: 3.9g
• Carbs: 18g
• Fiber: 0.7g
• Sugar: 4.1g

5. Sweet Potato Black Bean Casserole

Who says plant-based foods cannot be high in protein?

This vegetarian powerhouse combines the natural sweetness of roasted sweet potatoes with protein-rich black beans to give you a casserole with 23 grams of protein per serving.

The beauty of this dish is the balance of flavors and textures. Here, you get corn tortillas, cinnamon, sweet potatoes, cheddar, and cilantro.

Per Serving:

• Calories: 492
• Fats: 14g
• Protein: 23g
• Carbs: 71g
• Fiber: 15g
• Sugar: 9g

6. Buffalo Chicken Sweet Potato Casserole

What happens when you combine two comfort foods: buffalo chicken and mashed sweet potatoes? The results are this delicious casserole dish that offers 35 grams of protein per serving.

The sweet potatoes provide natural sweetness that balances the spicy buffalo sauce perfectly. And, it’s topped with melted cheese that is baked to golden perfection.

Per Serving:

• Calories: 443
• Fats: 22g
• Protein: 35g
• Carbs: 29g
• Fiber: 6.8g
• Sugar: 6.5g

7. Cheesy Philly Casserole

The classic Philly cheesesteak is one of the most addictive sandwiches out there. It’s rich, cheesy, and packed to the gills with protein. But it’s also fairly high in carbs!

If that’s not something you want, then this casserole is the best avenue to still enjoy these flavors.

Per Serving:

• Calories: 338
• Fats: 22g
• Protein: 28g
• Carbs: 6.7g
• Fiber: 1.3g
• Sugar: 2.6g

8. Sausage and Spinach Breakfast Casserole

Let’s kick things off with one of my go-to casserole recipes: a classic sausage and spinach combo. This is a delicious breakfast casserole, but you can enjoy it any time of the day.

I love using this to feed a crowd. It’s also great for meal prepping, since it keeps well in the fridge.

Per Serving:

• Calories: 407
• Fats: 31g
• Protein: 23g
• Carbs: 8.1g
• Fiber: 1.9g
• Sugar: 4g

9. Fajita Chicken Casserole

Source: cushyspa.com

Skip the tortillas and enjoy all your favorite fajita flavors in this low-carb, gluten-free casserole that packs 49 grams of protein per serving.

Each bite gives you perfectly seasoned chicken breasts, bell peppers, onions, and fajita seasoning. All wrapped with melted mozzarella cheese.

Because it wouldn’t be comfort food without gooey cheese.

Per Serving:

• Calories: 363
• Fats: 13g
• Protein: 49g
• Carbs: 10g
• Fiber: 2.5g
• Sugar: 3.8g

10. Zucchini Beef Casserole

Rich, savory, and incredibly satisfying. This casserole keeps net carbs under 5 grams while delivering 26 grams of protein per serving. It’s naturally gluten-free and guaranteed to keep hunger at bay for hours.

Ground beef mingles with melted cheese and tender zucchini, all brought together with aromatic seasonings that make every bite comforting and delicious.

Per Serving:

• Calories: 443
• Fats: 35g
• Protein: 26g
• Carbs: 6.1g
• Fiber: 1.2g
• Sugar: 2.6g

11. Teriyaki Chicken Casserole

Take your taste buds on an Asian-inspired journey with this Teriyaki casserole dish that delivers 35 grams of protein per serving. Here, you’ll get tender chicken pieces in a sweet and savory teriyaki sauce baked with rice and vegetables.

What makes this dish special is the homemade teriyaki sauce. It creates authentic flavors without all that excess sodium you get from store-bought options.

Per Serving:

• Calories: 428
• Fats: 3.7g
• Protein: 35g
• Carbs: 64g
• Fiber: 2.9g
• Sugar: 20g

12. Broccoli Cauliflower Casserole

This low-carb vegetable casserole packs 17 grams of protein per serving thanks to the cheese and cream. The combination of broccoli with cheese not only provides fiber and nutrients, but it also packs a punch of flavor.

Perfect for those who want to spice things up while following a keto or low-carb diet.

Per Serving:

• Calories: 388
• Fats: 32g
• Protein: 17g
• Carbs: 12g
• Fiber: 2.4g
• Sugar: 3.6g

13. Chicken Broccoli Bake

Sometimes simple is best, and this classic dish delivers 26 grams of protein per serving in the most comforting way. Tender chicken and broccoli mix in this creamy cheese sauce that is both rich and satisfying.

This is a great recipe for those picky eaters. I assure you that there won’t be a broccoli left behind.

Per Serving:

• Calories: 354
• Fats: 24g
• Protein: 26g
• Carbs: 8.9g
• Fiber: 2.4g
• Sugar: 2.8g

14. Tex Mex Casserole

Do you love southwestern flavors? This spicy casserole offers 20 grams of protein per serving and lots of flavor.

Ground beef, peppers, and cheese all combine with southwestern spices for a dish that’s both comforting and exciting. The blend of spices creates the most authentic Tex-Mex flavor you’ve ever tried.

Per Serving:

• Calories: 269
• Fats: 14g
• Protein: 20g
• Carbs: 16g
• Fiber: 3.6g
• Sugar: 1.8g

15. Stuffed Pepper Casserole

If you love stuffed veggies, this dish is for you.

Here, you’ll get the flavors of stuffed peppers without the individual preparation and with 23 grams of protein per serving. Every bite gives you ground beef, rice, peppers, and rich tomato sauce.

This casserole captures the essence of the classic dish without taking hours to prepare.

Per Serving:

• Calories: 386
• Fats: 7g
• Protein: 23g
• Carbs: 35g
• Fiber: 3.3g
• Sugar: 4.6g

16. Chicken Bacon Ranch Casserole

Source: wholesomeyum.com

Indulge in this rich and creamy casserole that delivers an impressive 37 grams of protein per serving. The combination of chicken, bacon, and ranch flavors creates ultimate comfort food that’s also surprisingly low in carbs.

What makes this casserole special is how it satisfies cravings for rich, indulgent flavors while giving you a nutritious meal.

Per Serving:

• Calories: 447
• Fats: 35.8g
• Protein: 37.3g
• Carbs: 6g
• Fiber: 1.6g
• Sugar: 1.3g

17. Healthy Chicken Broccoli Casserole

Source: ifoodreal.com

The last recipe I have for you is this healthy chicken broccoli casserole that gives you 18 grams of protein per serving. This version of the classic dish proves that you can still eat healthy while getting a flavorful meal.

Per Serving:

• Calories: 237
• Fats: 9g
• Protein: 18g
• Carbs: 22g
• Fiber: 2g
• Sugar: 3g

18. Sweet Potato and Ground Beef Casserole

Source: theroastedroot.net

This hearty casserole combines lean ground beef with sweet potatoes to offer you a dish with 30 grams of protein per serving. The natural sweetness of the potatoes perfectly balances the savory beef.

And, it’s all topped with grated cheese just to give it that extra hint of comfort.

Per Serving:

• Calories: 455
• Fats: 20g
• Protein: 30g
• Carbs: 38g
• Fiber: 4g
• Sugar: 7g

19. Ground Turkey Pasta Bake

Source: ifoodreal.com

Are you looking for a lighter meal that still offers you a lot of protein? This turkey-based casserole provides 28 grams of protein.

The delicious pasta is mixed with kale, parsley, mozzarella cheese, ground turkey, and spices like oregano, red pepper flakes, and rosemary. The end result is a delicious meal that has a unique flavor.

Per Serving:

• Calories: 348
• Fats: 9g
• Protein: 28g
• Carbs: 39g
• Fiber: 5g
• Sugar: 6g

20. Wild Rice Chicken Casserole

Source: theroastedroot.net

This rustic casserole combines tender chicken with nutty wild rice to give you 23 grams of protein per serving. The earthy flavors of wild rice pair beautifully with seasoned chicken and veggies.

But it’s not all about the flavors. The different textures create a unique experience that is going to make you want to go for seconds.

Per Serving:

• Calories: 379
• Fats: 16g
• Protein: 23g
• Carbs: 29g
• Fiber: 4g
• Sugar: 5g

21. Chicken and Butternut Squash Biscuit Casserole

Source: neighborfoodblog.com

Celebrate fall flavors with this seasonal casserole that offers 23 grams of protein per serving. Tender chicken and sweet butternut squash are topped with fluffy biscuits for a dish that represents autumn.

There is something special about the natural sweetness of butternut squash paired with savory chicken, and a melt-in-your-mouth biscuit.

Per Serving:

• Calories: 383
• Fats: 15g
• Protein: 23g
• Carbs: 40g
• Fiber: 4g
• Sugar: 6g